Carbohydrate-Binding Molecules with Non-Peptidic Skeletons
نویسندگان
چکیده
منابع مشابه
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models
Current treatments available for African sleeping sickness or human African trypanosomiasis (HAT) are limited, with poor efficacy and unacceptable safety profiles. Here, we report a new approach to address treatment of this disease based on the use of compounds that bind to parasite surface glycans leading to rapid killing of trypanosomes. Pradimicin and its derivatives are non-peptidic carbohy...
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ژورنال
عنوان ژورنال: Trends in Glycoscience and Glycotechnology
سال: 2012
ISSN: 0915-7352,1883-2113
DOI: 10.4052/tigg.24.1